Turkey Tetrazzini

Leftover Thanksgiving Turkey Recipe

by Alli

This shop, Turkey Tetrazzini, has been compensated by Collective Bias, Inc. and its advertiser. All opinions are mine alone. 

It’s beginning to look a lot like Thanksgiving and my head is filled with visions of deep-fried turkey, cornbread dressing, sweet potato casserole, and pecan pie.

I’ll have a house full of guests (16 total) on Thanksgiving Day and I can hardly wait for the feast to begin. Desserts will be made the day before and hidden in the fridge.

The table will be set the night before. I do everything I can in advance so that Thanksgiving Day is reserved for cooking the main event.

On Thanksgiving morning, while the family is enjoying mocha punch, cinnamon rolls, and watching the parade on TV, I’ll begin to prepare the turkey for deep frying. That’s how we roll in the south and I always buy a turkey large enough for leftovers to make Turkey Tetrazzini.

Turkey Tetrazzini - Made from leftover turkey

After The Thanksgiving Day Parade

After the parade, it’s football time! I keep my eye on my favorite team while I bake the cornbread for my famous cornbread dressing. Onions will be chopped, celery will be diced and delicious smells will begin to waft from the kitchen.

The key to making good dressing is using plenty of Swanson® Chicken Broth. I always use Swanson® because it’s made with simple ingredients.

Plus, it’s 100% natural and contains no added MSG, artificial flavors, or preservatives. I also add a can of Campbell’s® cream of mushroom soup to my dressing. It adds an extra layer of flavor and it’s my not-so-secret-anymore ingredient.

turkey Tetrazzini Made with Leftover Turkey

Helpful Hint: I also use Swanson® Chicken Broth and Campbell’s® Cream of Mushroom Soup when I make Turkey Tetrazinni, so I make sure to stock up when I’m shopping at Target.

Turkey Tetrazzini is the perfect meal for the day after Thanksgiving. It’s delicious and easy to make. It’s a great way to use up the leftover turkey.

Ingredients At A Glance

  • butter
  • Swanson® Chicken Broth
  • Campbell’s® Cream of Mushroom Soup
  • half and half
  • flour
  • shredded parmesan cheese 
  • 1 package (8 oz.) thin spaghetti
  • fresh, sliced mushrooms
  • cooked, chopped turkey (you’ll need three cups)

How to Make Turkey Tetrazzini

In a large skillet, sauté mushrooms in 2 Tablespoons of butter until softened. Remove mushrooms and set them aside.

How to make Turkey Tetrazzini

Next, we need to make a Béchamel (aka white) Sauce. It’s easy and I use the same recipe when I’m making homemade mac and cheese or potato soup.

In the same skillet, melt the remaining butter and add the flour. Whisk for one minute or until smooth.

Add butter and flour - Turkey Tetrazzini

Add the half and half and the Swanson® Chicken Broth and whisk until smooth and thickened.

How to Make Turkey Tetrazzini

Remove from the heat and add the parmesan cheese and Campbell’s® Cream of Mushroom Soup.

How to Make Turkey Tetrazzini

Combine the sauce mixture with the turkey and spaghetti.

Turkey Tetrazzini

Place in a greased baking dish and sprinkle with remaining parmesan cheese. Bake at 350º for 20-25 minutes or until lightly browned and bubbly. Serve with a salad and you’re good to go.

How to Make Turkey Tetrazzini


Yield: 6-8 servings

Turkey Tetrazzini

How to Make Turkey Tetrazzini

Turkey Tetrazzini is creamy and delicious - the perfect way to serve leftover turkey.

Prep Time 10 minutes
Cook Time 40 minutes
Total Time 50 minutes


  • 6 Tablespoons butter
  • 2 cups Swanson® Chicken Broth
  • 1 can Campbell's® Cream of Mushroom Soup
  • 3/4 cup half and half
  • 4 Tablespoons flour
  • 1/2 cup shredded parmesan cheese plus 1 Tablespoon, divided
  • 1 package (8 oz.) thin spaghetti
  • 1 (8 oz.) package fresh, sliced mushrooms
  • 3 cups cooked, chopped turkey


  1. Preheat oven to 350º.
  2. Cook spaghetti according to package directions.
  3. Heat 2 Tablespoons butter in a large skillet and add mushrooms. Sauté on medium heat for 5-6 minutes. Set aside.
  4. Add the remaining butter to the skillet, add flour and whisk for one minute or until smooth.
  5. Add half and half and chicken broth and stir until smooth and thickened.
  6. Remove from heat and stir in the cream of mushroom soup, mushrooms and 1/2 cup parmesan cheese.
  7. Add the chopped turkey and spaghetti.
  8. Transfer to a lightly greased 2-quart baking dish. Top with remaining tablespoon parmesan cheese and bake for 20-25 minutes or until light brown and bubbly.

Nutrition Information



Serving Size


Amount Per Serving Calories 317Total Fat 19gSaturated Fat 10gTrans Fat 1gUnsaturated Fat 8gCholesterol 94mgSodium 732mgCarbohydrates 14gFiber 1gSugar 4gProtein 21g

Did you make this recipe?

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What’s your favorite way to use Thanksgiving Day leftovers?

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Fi Ni Neachtain November 21, 2016 - 6:57 am

That looks so delicious, a perfect dinner option. I always wonder what to do with the leftover turkey – apart from turkey sandwiches – so I’d love to give this a try.

zan November 21, 2016 - 8:13 am

I used to make Tetrazzini a lot when I lived in Greenville. But I always had to find a recipe online. I don’t like them dry and this one certainly looks delish. That sauce is surely making all the difference and I love that you could use it to make mac and cheese and such. Pinning because I need a good sauce recipe for meals like these!!! I don’t have one favorite to meal to make with left over turkey. It’s just whatever comes to mind!!

Maureen @Scoops of Joy November 21, 2016 - 8:35 am

OMG I get hungry just reading this! It looks so delicious and so easy to make. It’s been 8 years since the last time I had a real Thanksgiving meals.

Jeanette November 21, 2016 - 8:59 am

I LOVE TurkeyTetrazzini! I totally forgot about it! I will be doing this with left overs for sure!! YUM!!

ricci November 21, 2016 - 9:30 am

I usually make Turkey Tetrazzini with my turkey leftovers as well! YUM!!

David @ Spiced November 21, 2016 - 1:26 pm

We typically just turn leftovers into some awesome sandwiches…but I gotta say this tetrazzini sounds awesome! I might just have to put aside some leftover turkey this year for this leftover awesomeness! Thanks for sharing. #client

Jenn @ EngineerMommy November 21, 2016 - 1:58 pm

This recipe looks and sounds so delicious. I can’t wait to try this recipe. We will definitely have a lot of leftover turkey after Thanksgiving.

Sarah Bailey November 21, 2016 - 1:59 pm

Ohh now this sounds like a great way to use your left overs – absolutely delicious and not too much hard work either! x

Anosa November 21, 2016 - 2:34 pm

Now this is one yummy way of making use of the left over turkey. I feel like I should celebrate thanksgiving too even though we don’t celebrate in the UK

Dee November 21, 2016 - 4:34 pm

OMG! I remember eating this growing up at my Grandmother’s house, but I never knew the name of it. Thank you so much for sharing the recipe I am so excited that I am going to have to try this out tonight with chicken.

Vera Sweeney November 21, 2016 - 4:40 pm

What a great way to use up leftover turkey!! I know we always seem to have way to many left over it seems even with careful planning.

Pam November 21, 2016 - 8:05 pm

I had chicken tetrazzini not too long ago, but I never thought of making it with turkey. What a great way to use up leftover Thanksgiving turkey.

lisa November 21, 2016 - 8:35 pm

Turkey tetrazzini sounds so amazing. I have never tried making it, but I love chicken tetrazzini so I imagine it is just as good!

Paula Bendfeldt November 21, 2016 - 9:11 pm

This looks delicious. Sounds like a great recipe to make with those turkey leftovers. Love pasta!

Victoria November 22, 2016 - 5:49 am

Nice detailed recipe.. Looks so delicious brilliant idea to use the left over turkey.. I really love to eat pasta..

Lorelai @ Life With Lorelai November 22, 2016 - 10:43 am

Ooh, this look delish! I love how simple it is. Swanson broths and Campbell’s soups always come in so handy for things. I am going to make this. 🙂 We like to do turkey stuffing and cranberry paninis with our leftovers. Thanksgiving = YUM!

Life With Lorelai

Chubskulit Rose November 23, 2016 - 6:55 am

This sounds and look delicious. We’re not very fond of turkey so I wonder if this would work with leftover ham?

Sara November 23, 2016 - 1:27 pm

This looks fantastic! I will definitely be trying this recipe with our leftovers!

lynzy November 23, 2016 - 11:37 pm

This is such a great recipe idea for leftovers! I love this!! Yum!

christina aliperti November 24, 2016 - 4:50 am

We usually make a turkey soup but this looks yummy. I think I will try it this week with leftovers.

Mommy Levy December 12, 2016 - 8:58 pm

now this makes me hungry. This looks yummy!


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